-High density, speculated mass
-Clustered micro calcifications with variable shape and size; Granular, bizarre micro calcifications are suspicious.
-Well-defined solid masses are sometimes malignant. (Ultrasound is used to determine whether such a mass is solid or cystic).
Secondary Signs of Malignancyarchitectural distortion
focally dilated duct
If mammography detects a non-palpable but suspicious-appearing lesion, needle localization and excisional biopsy or steriotaxic (computer guided) core biopsy can be used to sample the suspicious area. Most mammographers seek a 20-30% positive rate for biopsies of mammographically demonstrated abnormalities.